Last Updated on April 25, 2026 by Beth Skwarecki
Mylanta and Pepto can both help upset stomach symptoms, but they work in different ways. I would use Mylanta more for heartburn, acid indigestion, and gas. I would think of Pepto more for nausea, diarrhea, and stomach upset.
The better option depends on your symptoms.
What Mylanta Is Better For
Mylanta is often used for
- heartburn
- acid indigestion
- sour stomach
- gas
- bloating
It works by neutralizing stomach acid and helping gas pass more easily.
What Pepto Is Better For
Pepto is often used for
- nausea
- diarrhea
- upset stomach
- mild stomach infection symptoms
It works differently and is usually better when diarrhea or nausea is the main issue.
Which One Is Better For Diarrhea
Pepto is usually the better choice for diarrhea.
Mylanta may actually worsen diarrhea in some people because magnesium can loosen stool.
If bowel changes are your main concern, read Does Mylanta Cause Diarrhea before choosing.
Which One Is Better For Heartburn
Mylanta is usually the better option for heartburn and acid indigestion because it is designed to reduce stomach acid.
Bottom Line
Mylanta is usually better for heartburn and gas. Pepto is usually better for nausea and diarrhea. Your best choice depends on what symptom you are trying to treat.
Beth is Cloudmineinc’s senior health editor and a certified personal trainer. She has over 10 years experience as a science journalist and is the author of two books. She deadlifts over 315 lbs.